Nanosuspension: Potential Applications of Nano Therapeutics in Ocular Delivery
نویسندگان
چکیده
منابع مشابه
Therapeutics Applications of Nanosuspension in Topical/ Mucosal Drug Delivery
During the last two decades, many modern technologies have been established in the pharmaceutical research and development area. The automation of the drug discovery process by technologies such as high-throughput screening, combinatorial chemistry, and computer-aided drug design is leading to a vast number of drug candidates possessing a very good efficacy [1]. Unfortunately, many of these dru...
متن کاملTherapeutics Applications of Nanosuspension in Topical/ Mucosal Drug Delivery
During the last two decades, many modern technologies have been established in the pharmaceutical research and development area. The automation of the drug discovery process by technologies such as high-throughput screening, combinatorial chemistry, and computer-aided drug design is leading to a vast number of drug candidates possessing a very good efficacy [1]. Unfortunately, many of these dru...
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Objective(s): The aim of this study was to prepare a nanosuspension formulation as a new vehicle for the improvement of the ocular delivery of vitamin A. Material and Methods: Formulations were designed based on full factorial design. A high pressure homogenization technique was used to produce nanosuspensions. Fifteen formulations were prepared by the use of different combinations of surfa...
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Nucleic acid-based therapeutics have gained a lot of interest for the treatment of diverse ophthalmic pathologies. The first to enter in clinic has been an oligonucleotide, Vitravene(®) for the treatment of cytomegalovirus infection. More recently, research on aptamers for the treatment of age related macular degeneration has led to the development of Macugen(®). Despite intense potential, effe...
متن کاملPolymeric ocular nanosuspension for controlled release of acyclovir: in vitro release and ocular distribution
The aim of this study is to formulate a novel ophthalmic nanosuspension (ONS), an alternative carrier system to traditional colloidal carriers for controlled release (CR) of acyclovir (ACV). In the present study, ONS is employed to avoid some of major disadvantages of colloidal carriers systems such as instability in cul de sac and short half life by increasing efficiency of drug encapsulation ...
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ژورنال
عنوان ژورنال: Modern Applications of Bioequivalence & Bioavailability
سال: 2018
ISSN: 2577-2856
DOI: 10.19080/mabb.2018.03.555608